Travel by Ferry
There is a ferry connection between Lipsi and Athens, as ferries depart from Piraeus port about 3 times a week. However, the trip is quite long and it lasts approximately 9 hours.
If you want to travel from Athens to Lipsi, then it might be more convenient for you to reach Leros by plane and then travel to Lipsi by ferry.
Apart from Athens and Leros, Lipsi is also connected by ferry with Rhodes, Kos, Kalymnos and more.