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There is no airport in Mesolongi. The closest airport is located in Patra, located on the northern side of Peloponnese. The airport of Patra (Araxos) works only in summer and does not operate domestic flights. It operates only charter and low-cost flights from Europe. In particular, the popular low-cost air company Ryan Air operates flights to Patra in summer.
Visitors can go from Patra to Mesolongi by bus or rental car. The airport of Patra is located in the region of Araxos, 10 km from the city center. As buses to Mesolongi depart from the center of Patra, tourists have to take a taxi from the airport to the city center.