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There is no airport on Agistri island. The International Airport of Athens is the closest to Agistri island and it receives flights from all Greek islands and from all the world.
From the port of Piraeus in Athens, there is several ferries to Agistri every day. The trip from Piraeus to Agistri (port of Skala) by normal ferry is 2 hours and by hydrofoil (port of Myli) is 50 min.
From Athens airport, you can organize your Athens airport transfer online to Piraeus port.